This inventor holds 2 USPTO granted patents. Top assignees: Agency of Industrial Science and Technology, Extra Ministerial Bureau of Ministry of International Trade and Industry, Ministry of International Trade & Industry. Active years: 1991-1992.
Company Filing History:
2 out of 1,430 
1 out of 4 
1 out of 348 Years Active: 1991-1992
Title: Akiko Akaoka: Innovator in Protein Production
Introduction
Akiko Akaoka is a prominent inventor based in Mobara, Japan. She has made significant contributions to the field of biotechnology, particularly in the area of protein production using Bacillus subtilis strains. With a total of 2 patents, her work has the potential to enhance the efficiency of protein accumulation in culture mediums.
Latest Patents
Akaoka's latest patents focus on the development of Bacillus subtilis strains with modified extracellular protease activities. One of her notable inventions involves a strain whose extracellular protease activities can be reduced by introducing a gene that stimulates extracellular protease levels into its genomic DNA. This innovative approach allows for the efficient production and accumulation of desired proteins, such as human growth hormone, in large amounts. The treatment can increase the accumulation level of human growth hormone secreted by a B. subtilis MT-430 strain carrying recombinant DNA phGH427 by five to tenfold. Another patent describes the construction of an expression-secretion vector that enhances the extracellular production of proteins by utilizing specific DNA sequences involved in gene expression and protein secretion.
Career Highlights
Throughout her career, Akaoka has worked with various organizations, including the Agency of Industrial Science and Technology and the Extra Ministerial Bureau of the Ministry of International Trade and Industry. Her expertise in biotechnology has positioned her as a key figure in the advancement of protein production technologies.
Collaborations
Akaoka has collaborated with notable colleagues in her field, including Yoshio Furutani and Akira Nakayama. These partnerships have contributed to her innovative research and development efforts.
Conclusion
Akiko Akaoka's work in the field of biotechnology, particularly her advancements in protein production using Bacillus subtilis strains, showcases her innovative spirit and dedication to scientific progress. Her contributions are paving the way for more efficient methods of protein accumulation, which could have significant implications in various industries.