Company Filing History:
Years Active: 2002
Title: Ailing Li: Innovator in Antiviral Compounds
Introduction
Ailing Li is a notable inventor based in Carol Stream, Illinois, who has made significant contributions to the field of antiviral compounds. With a total of two patents to his name, Li's work focuses on innovative methods for preparing calanolide compounds, which have potential applications in antiviral therapies.
Latest Patents
Li's latest patents involve methods for preparing 2,2-dimethyl-5-acyloxy-10-propyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-8-one and 2,2-dimethyl-5-hydroxy-10-propyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-8-one. These compounds serve as intermediates for synthesizing antiviral calanolide compounds. For instance, the Fries rearrangement on compound 5 or the Friedel-Crafts reaction on compound 6 yields an intermediate that can be converted to calanolide A and calanolide B. The coupling of compound 6 with a suitable chiral molecule under Mitsunobu or nucleophilic displacement facilitates the asymmetric synthesis of these antiviral compounds.
Career Highlights
Ailing Li is currently associated with Sarawak Medichem Pharmaceuticals, Inc., where he continues to advance his research in antiviral compounds. His innovative approaches have garnered attention in the pharmaceutical industry, contributing to the development of effective antiviral therapies.
Collaborations
Li has collaborated with notable coworkers, including Ze-Qi Xu and Hongwei Yuan, who have supported his research endeavors in the field of antiviral compounds.
Conclusion
Ailing Li's contributions to the field of antiviral compounds through his innovative patents highlight his role as a significant inventor in the pharmaceutical industry. His work continues to pave the way for advancements in antiviral therapies.