This inventor holds 4 USPTO granted patents and 1 published patent application, plus 1 CIPO patent. Top assignee: The Feinstein Institutes for Medical Research. Active years: 2022-2026.
Company Filing History:
Years Active: 2022-2026
Title: Ahmad Altiti: Innovator in Thiosemicarbazates and Peptidomimetics
Introduction
Ahmad Altiti is a notable inventor based in Manhasset, NY (US). He has made significant contributions to the field of chemistry, particularly in the development of thiosemicarbazates and their applications in drug discovery and synthesis.
Latest Patents
Ahmad Altiti holds a patent for "Thiosemicarbazates and uses thereof." This patent encompasses a range of compounds including thioesters, thiocarbamates, thiocarbazates, semithiocarbazates, peptides, aza-amino acid conjugates, and azapeptides. The patent also describes a chemoselective and site-specific functionalization protocol of protected thiocarbazates and semithiocarbazates. This innovative protocol utilizes the Mitsunobu reaction to selectively alkylate the nitrogen atom adjacent to the acylthiol moiety with alcohols. The result is the production of protected mono-substituted thiocarbazates that can be stored for extended periods. These compounds can be activated under mild conditions at low temperatures using halonium reagents, allowing for the integration into substituted semicarbazides. These semicarbazides serve as synthons in the synthesis of aza-amino acid conjugates, azapeptides, and other peptidomimetics. Additionally, the patent outlines methods for preparing and utilizing ureases, carbazides, semicarbazides, beta-peptides, azapeptides, and their conjugates in various medical applications.
Career Highlights
Ahmad Altiti is currently affiliated with the Feinstein Institutes for Medical Research. His work focuses on the intersection of chemistry and medicine, contributing to advancements in drug discovery and therapeutic applications.
Collaborations
Ahmad collaborates with Yousef Al-Abed, enhancing the research and development efforts in their field.
Conclusion
Ahmad Altiti's innovative work in thiosemicarbazates and peptidomimetics showcases his commitment to advancing medical research and drug discovery. His contributions are paving the way for new therapeutic solutions.