Ah Wah Lam

Title: Ah Wah Lam - Innovator in Predictive Liver Injury Assessment

Introduction

Ah Wah Lam is a notable inventor based in Singapore, recognized for his contributions to the field of predictive medicine. His innovative work focuses on developing methods to assess liver injury caused by various compounds, which is crucial for drug safety and development.

Latest Patents

Ah Wah Lam holds a patent for a "High throughput method for accurate prediction of compound-induced liver injury." This method and system provide a way to predict liver injury in vivo due to hepatocyte damage by a test compound. The process involves acquiring images of fluorescently stained cells from a cell culture treated with a range of doses of the test compound and its vehicle. The method includes segmenting the acquired images and extracting phenotypic features such as intensity, textural, morphological, and ratiometric features. These features are analyzed to predict the probability of liver injury based on machine learning methods.

Career Highlights

Ah Wah Lam is affiliated with the Agency for Science, Technology and Research, where he applies his expertise in predictive analytics and liver health. His work is instrumental in advancing the understanding of hepatocyte responses to various compounds, thereby enhancing drug safety assessments.

Collaborations

Ah Wah Lam collaborates with talented individuals such as Daniele Zink and Nur Faezah Begum Akbar Hussain, contributing to a dynamic research environment focused on innovative solutions in liver injury prediction.

Conclusion

Ah Wah Lam's innovative approach to predicting liver injury represents a significant advancement in the field of medical research. His contributions are vital for improving drug safety and understanding hepatocyte responses to various compounds.