This inventor holds 2 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignee: Universitéde Liége. Active years: 2010-2017.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Durbuy, BE (2010)
- Liège, BE (2017)
Company Filing History:
Years Active: 2010-2017
Title: Agnès Noel: Innovator in Cancer Treatment and Bronchial Inflammatory Diseases
Introduction
Agnès Noel is a prominent inventor based in Liège, Belgium. He has made significant contributions to the field of medical treatments, particularly in cancer therapy and bronchial inflammatory diseases. With a total of 2 patents, his work has the potential to impact many lives.
Latest Patents
One of Agnès Noel's latest patents focuses on a combination treatment for cancer. This invention provides a method using an MT4-MMP inhibitor and an EGFR inhibitor for the treatment of cancer. The MT4-MMP inhibitor and EGFR inhibitor are distinct from one another. MT4-MMP, also known as MMP-17, is a glycosylphosphatidyl inositol (GPI) anchored MMP produced by cancer cells. It promotes tumor vascularization and metastases. The invention reveals that MT4-MMP expression enhances cancer cell proliferation through mechanisms involving retinoblastoma protein (Rb) inactivation, cyclin-dependent kinase CDK4 activation, and Epidermal Growth Factor Receptor (EGFR) signaling. Co-immuno-precipitations indicate the presence of protein complexes containing both MT4-MMP and EGFR. Furthermore, the invention uncovers a novel mechanism of MT4-MMP action through outside-in signaling involving EGFR, identifying an unexpected crosstalk between an MMP and EGFR as a key driver of cancer cell biology.
Another significant patent by Agnès Noel involves the use of cyclodextrin for the treatment and prevention of bronchial inflammatory diseases, particularly asthma. This invention provides a cyclodextrin compound for the manufacturing of a medicament aimed at addressing these conditions.
Career Highlights
Agnès Noel is affiliated with the Université de Liège, where he continues to advance his research and innovations. His work is characterized by a strong focus on developing effective treatments for serious health issues.
Collaborations
Agnès has collaborated with notable colleagues such as Jean-Michel Foidart and Didier Cataldo, contributing to the advancement of medical research and innovation.
Conclusion
Agnès Noel is a dedicated inventor whose work in cancer treatment and bronchial inflammatory diseases showcases his commitment to improving healthcare. His innovative patents reflect a deep understanding of complex biological mechanisms
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile