Company Filing History:
Years Active: 1998-2001
Title: Abul Mandal: Innovator in Trehalose Production
Introduction
Abul Mandal is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of biotechnology, particularly in the production of trehalose, a sugar that plays a crucial role in stress tolerance for various organisms. With a total of 3 patents, Mandal's work has the potential to impact food storage and agricultural practices.
Latest Patents
One of Mandal's latest patents focuses on increasing the trehalose content of organisms by transforming them with combinations of the structural genes for trehalose synthase. This innovation involves isolating and cloning two nucleotide sequences encoding different polypeptides found in yeast trehalose synthase. Additionally, a third polypeptide has been characterized, and a method has been developed to isolate and clone the nucleotide sequence encoding this polypeptide. The coding sequences can be inserted into suitable vectors and used to transform host cells. The transformed cells are expected to produce increased amounts of trehalose compared to untransformed wild types, enhancing their tolerance to various stresses, particularly reduced water availability. This invention may improve the stress tolerance of organisms, extend the storage life of foodstuffs, and enable the economical production of trehalose on an industrial scale using traditional foodstuffs like baker's yeast.
Career Highlights
Throughout his career, Abul Mandal has worked with various companies, including Btg International Limited. His innovative approaches have garnered attention in the biotechnology sector, leading to advancements in the production and application of trehalose.
Collaborations
Mandal has collaborated with notable individuals in his field, including John Londesborough and Tapio Palva. These partnerships have contributed to the development and refinement of his inventions.
Conclusion
Abul Mandal's work in trehalose production exemplifies the intersection of innovation and biotechnology. His patents hold promise for enhancing stress tolerance in organisms and improving food storage solutions.