Location History:
- Columbus, OH (US) (1992)
- Westerville, OH (US) (1995)
Company Filing History:
Years Active: 1992-1995
Title: Innovations of Abul K Anisuzzaman in Boron Neutron Capture Therapy
Introduction
Abul K Anisuzzaman is a notable inventor based in Columbus, OH (US). He has made significant contributions to the field of boron neutron capture therapy through his innovative patents. His work focuses on developing novel boron-containing nucleosides and amino acids that can be utilized in treating tumor cells.
Latest Patents
Anisuzzaman holds two patents that highlight his groundbreaking research. The first patent, titled "Carboranyl uridines and their use in boron neutron capture therapy," relates to novel boron-containing nucleosides and amino acids. This invention utilizes the enzymatic systems in tumor cells to incorporate boron-containing structures into nucleic acids and proteins. The subsequent use of boron neutron capture therapy provides a method for effectively treating tumor cells. The second patent, "2' and 3' Carboranyl uridines and their diethyl ether adducts," discloses a process for preparing carboranyl uridine nucleoside compounds and their diethyl ether adducts. These compounds exhibit a tenfold increase in boron content compared to prior art boron-containing nucleoside compounds. They also demonstrate enhanced lipophilicity and hydrophilic properties, which are essential for solvation in aqueous media for incorporation in boron neutron capture therapy methods.
Career Highlights
Anisuzzaman is affiliated with The Ohio State University, where he continues to advance his research in the field of cancer treatment. His innovative work has positioned him as a key figure in the development of therapeutic methods that leverage boron compounds.
Collaborations
Throughout his career, Anisuzzaman has collaborated with esteemed colleagues, including Albert H Soloway and Rolf F Barth. These collaborations have further enriched his research and contributed to the advancement of boron neutron capture therapy.
Conclusion
Abul K Anisuzzaman's contributions to the field of boron neutron capture therapy through his innovative patents demonstrate his commitment to advancing cancer treatment. His work continues to inspire future research and development in this critical area of medicine.