Company Filing History:
Years Active: 2024-2025
Title: Abraham S. Weintraub: Innovator in Gene Expression Regulation
Introduction
Abraham S. Weintraub is a prominent inventor based in Somerville, MA (US). He has made significant contributions to the field of gene expression regulation, holding 2 patents that focus on innovative methods for altering gene expression.
Latest Patents
Weintraub's latest patents include groundbreaking work on the regulation of transcription through CTCF loop anchors. This invention discloses methods for altering the expression of a gene with a promoter region CTCF binding site. It also includes compositions and methods useful for treating diseases or conditions involving over-expression or under-expression of such genes. Additionally, the patent covers cells and non-human animals with modified promoter region CTCF binding sites, along with methods for screening compounds that can modify gene expression.
Another significant patent by Weintraub involves methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops. This invention relates to modulating the expression of one or more genes in a cell by influencing the multimerization of a transcription factor and the formation of enhancer-promoter DNA loops. It also addresses treating diseases and conditions associated with aberrant gene expression through similar modulation techniques.
Career Highlights
Abraham S. Weintraub is affiliated with the Whitehead Institute for Biomedical Research, where he continues to advance research in gene regulation and expression. His work has been instrumental in developing new therapeutic strategies for various genetic conditions.
Collaborations
Weintraub has collaborated with notable scientists in his field, including Richard A. Young and Charles H. Li. These collaborations have further enriched his research and contributed to the advancement of knowledge in gene expression regulation.
Conclusion
Abraham S. Weintraub is a distinguished inventor whose work in gene expression regulation has the potential to impact medical science significantly. His innovative patents and collaborations highlight his commitment to advancing the understanding and treatment of genetic conditions.