Abhishek Sharma

Title: Abhishek Sharma and Green Synthesis of Medicinally Important Compounds.

Introduction

Abhishek Sharma is an inventor based in Himachal Pradesh, India, whose patent work includes a microwave-assisted method for synthesizing medicinally important aldehydes. He is associated with the Council of Scientific and Industrial Research. His listed portfolio includes 3 patents.

Latest Patents

One of Sharma’s listed inventions is titled “Microwave Induced Single Step Green Synthesis of Some Novel 2-Aryl Aldehydes and Their Analogues.” It describes a single-step process for preparing 2-aryl and 2,2-diaryl aldehydes and related compounds from readily available aryl alkenes.

The method uses microwave or conventional heating and aqueous reaction conditions, with reagents such as N-bromosuccinimide, N-iodosuccinimide, or N-chlorosuccinimide. Depending on the conditions, the reaction takes between one and 30 minutes. The process is designed to avoid intermediate epoxide formation and the use of transition-metal catalysts or Lewis acids and bases.

The resulting aldehydes are useful intermediates for compounds associated with medicines such as naproxen and flurbiprofen, as well as anticancer drug candidates such as phenstatin. The patent describes the approach as an alternative to conventional multistep methods, reporting yields of 35–55% depending on the solvent and substrate.

Career Highlights

Sharma’s listed patent work focuses on synthetic chemistry and a more direct route to compounds with potential pharmaceutical applications. The invention emphasizes readily available starting materials and reaction conditions intended to reduce reliance on certain expensive or hazardous catalysts and reagents.

Collaborations

The supplied information identifies Arun Kumar Sinha and Rakesh Kumar as Sharma’s coworkers. It does not specify their individual roles in the patent or related research.

Conclusion

Abhishek Sharma’s listed invention presents a concise, microwave-assisted approach to preparing medicinally relevant aldehydes, reflecting his contribution to synthetic chemistry research associated with the Council of Scientific and Industrial Research.