Davis, CA, United States of America

Aaron Wecksler


Average Co-Inventor Count = 4.8

ph-index = 2

Forward Citations = 7(Granted Patents)


Company Filing History:


Years Active: 2015

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2 patents (USPTO):Explore Patents

Title: Innovations of Aaron Wecksler in Pain Management and Angiogenesis

Introduction

Aaron Wecksler is an accomplished inventor based in Davis, CA (US). He has made significant contributions to the field of pharmacology, particularly in the development of compounds that target pain management and angiogenesis. With a total of 2 patents, Wecksler's work is paving the way for new therapeutic options.

Latest Patents

Wecksler's latest patents include innovative compounds such as pyrazole inhibitors of COX-2 and sEH. These compounds are designed to provide dual inhibition, which has shown superior anti-allodynic activity compared to existing treatments like celecoxib and t-AUCB. The compounds have demonstrated effectiveness in a lipopolysaccharide (LPS) induced model of pain in rats. Additionally, these dual inhibitors exhibit potent anti-angiogenic effects, slowing breast tumor growth in vivo and inhibiting angiogenesis in various settings.

Another notable patent involves sorafenib derivatives as sEH inhibitors. This invention focuses on compounds that inhibit soluble epoxide hydrolase, addressing associated disease conditions. The innovative nature of these compounds highlights Wecksler's commitment to advancing medical science.

Career Highlights

Wecksler is affiliated with the University of California, where he continues to engage in groundbreaking research. His work is characterized by a focus on developing novel therapeutic agents that can significantly improve patient outcomes in pain management and cancer treatment.

Collaborations

Wecksler collaborates with esteemed colleagues such as Bruce D Hammock and Sung Hee Hwang. Their combined expertise enhances the research and development of innovative solutions in their respective fields.

Conclusion

Aaron Wecksler's contributions to the field of pharmacology through his patents reflect his dedication to innovation and improving healthcare. His work on dual inhibitors and sEH inhibitors showcases the potential for new treatments in pain management and cancer therapy.

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