This inventor holds 1 USPTO granted patent. Top assignee: Centers for Disease Control and Prevention. Active years: 2001.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2001
Title: A Michael Frace: Innovator in Influenza Vaccine Development
Introduction
A Michael Frace is a notable inventor based in Atlanta, GA, who has made significant contributions to the field of vaccine development. His work primarily focuses on the preparation and use of recombinant influenza A virus M2 construct vaccines. With a single patent to his name, Frace's innovations are aimed at improving public health and combating influenza A infections.
Latest Patents
Frace holds a patent titled "Preparation and use of recombinant influenza A virus M2 construct vaccines." This invention provides a method for increasing the recombinant expression and solubility of the influenza A virus M2 polypeptide. The patent details the use of nucleic acids encoding variants of the M2 protein, which have had transmembrane and other hydrophobic domains deleted. The resulting purified polypeptides are immunogenic and exhibit reduced hydrophobicity compared to the full-length M2 protein. Additionally, the patent outlines vaccines that incorporate these M2 variants expressed in prokaryotic hosts, as well as methods for preventing influenza A infections using these vaccines. It also discusses antibodies raised against the M2 variants and their applications in the diagnosis and treatment of influenza A infections.
Career Highlights
Frace is affiliated with the Centers for Disease Control and Prevention, where he applies his expertise in vaccine research and development. His work is crucial in the ongoing efforts to enhance vaccine efficacy and safety, particularly in the context of influenza A.
Collaborations
Frace has collaborated with esteemed colleagues such as Alexander I Klimov and Jacqueline M Katz, contributing to a collective effort in advancing vaccine technology and public health initiatives.
Conclusion
A Michael Frace's innovative work in the field of influenza vaccine development exemplifies the importance of scientific research in combating infectious diseases. His contributions are vital for improving vaccine strategies and enhancing public health outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile