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For the Inventor, By the Inventor

San Diego, CA, United States of America

Signal Pharmaceuticals, Inc.


USPTO Granted Patents = 169



Forward Citations = 1,426

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216 inventors (with patents filed for the assignee):

goldMedal John J Sapienza (25 out of 38 patents)

silverMedal Yoshitaka Satoh (23 out of 26 patents)

bronzeMedal Jan Elsner (22 out of 22 patents)

4.  Shuichan Xu (21 out of 26 patents)

5.  Heather K Raymon (21 out of 23 patents)

6.  Deborah Mortensen (20 out of 21 patents)

7.  Jennifer Riggs (20 out of 20 patents)

8.  Patrick Papa (19 out of 25 patents)

9.  Jingjing Zhao (19 out of 19 patents)

10.  Shripad S Bhagwat (19 out of 43 patents)

11.  Jason Parnes (18 out of 18 patents)

12.  Marianne Sloss (17 out of 17 patents)

13.  Sophie Perrin-Ninkovic (16 out of 18 patents)

14.  Roy Leonard Harris, Iii (16 out of 17 patents)

15.  Dehua Huang (15 out of 45 patents)


Core Competencies:
Substituted Aminopurine Compounds
Thienopyranones
mTOR Kinase Inhibitors
Dihydropyrazino-Pyrazines
Checkpoint Inhibitors
Solid Forms
Pharmaceutical Compositions
Cancer Treatment
Heterocyclic Compounds
Combination Therapy
Isotopologues

169 patents:

1. 12129237 - Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith (2024-10-29),
2. 11760762 - Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors (2023-09-19),
3. 11590139 - Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith (2023-02-28),
4. 11492332 - Isotopologues of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide (2022-11-08),
5. 11472814 - Thienopyranones and furanopyranones as checkpoint inhibitors and modulators of anti-tumor immunity (2022-10-18),
6. 11325890 - Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith (2022-05-10),
7. 11292796 - Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors (2022-04-05),
8. 11241430 - Solid forms of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide, compositions thereof and methods of their use (2022-02-08),
9. 11166950 - Treatment of cancer with TOR kinase inhibitors (2021-11-09),
10. 10975039 - Isotopologues of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide (2021-04-13),
11. 10940152 - Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith (2021-03-09),
12. 10919865 - Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith (2021-02-16),
13. 10689351 - Isotopologues of 2-(tert butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide (2020-06-23),
14. 10683298 - Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors (2020-06-16),
15. 10646493 - Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith (2020-05-12),
Signal Pharmaceuticals, Inc. is a biotechnology company specializing in the discovery and development of innovative therapeutics for various diseases. With a focus on signal transduction pathways, our team is dedicated to advancing drug candidates that can address unmet medical needs. By harnessing the power of molecular biology and targeted interventions, we aim to deliver breakthrough solutions that improve patients' lives.
This text is generated by artificial intelligence and may not be accurate.

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USPTO Data Jan 1 1976 - Dec 30 2025

169 Patents

#33 in San Diego, CA

#521 in California

#2,285 in US

#4,754 in the World

...
San Diego, CA, United States of America

Signal Pharmaceuticals, Inc.

Forward Citations = 1,426

216 inventors:

goldMedal John J Sapienza (25 out of 38 patents)

silverMedal Yoshitaka Satoh (23 out of 26 patents)

bronzeMedal Jan Elsner (22 out of 22 patents)

4.  Shuichan Xu (21 out of 26 patents)

5.  Heather K Raymon (21 out of 23 patents)

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