The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Jun. 13, 2012
Applicants:
Tsafi Pe'ery, Montclair, NJ (US);
Michael B. Mathews, Montclair, NJ (US);
Mainul Hoque, North Arlington, NJ (US);
Hartmut M. Hanauske-abel, Edgewater, NJ (US);
Inventors:
Tsafi Pe'ery, Montclair, NJ (US);
Michael B. Mathews, Montclair, NJ (US);
Mainul Hoque, North Arlington, NJ (US);
Hartmut M. Hanauske-Abel, Edgewater, NJ (US);
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4412 (2006.01); A61K 31/7105 (2006.01); A61K 31/7064 (2006.01); A61K 31/4375 (2006.01); A61K 45/06 (2006.01); A61K 31/4418 (2006.01); A61K 31/502 (2006.01); A61K 31/5025 (2006.01); A61K 31/7036 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 31/4375 (2013.01); A61K 31/4412 (2013.01); A61K 31/4418 (2013.01); A61K 31/502 (2013.01); A61K 31/5025 (2013.01); A61K 31/7036 (2013.01); A61K 31/7048 (2013.01); A61K 31/7064 (2013.01); A61K 45/06 (2013.01);
Abstract
Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD an inhibitor of NMD and a nonsense suppressor, whereby degradation of NMD susceptible mRNA is decreased and translation termination at a misplaced nonsense codon is blocked.