The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Apr. 19, 2016
Applicants:

International Aids Vaccine Initiative, New York, NY (US);

The Scripps Research Institute, La Jolla, CA (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

John Mascola, Rockville, MD (US);

Dennis R. Burton, La Jolla, CA (US);

Wayne Koff, Stony Brook, NY (US);

Peter Kwong, Washington, DC (US);

Gary Nabel, Washington, DC (US);

Sanjay K. Phogat, Edison, NJ (US);

Pascal Raymond Georges Poignard, San Diego, CA (US);

Melissa Danielle De Jean St. Marcel Simek-Lemos, Brooklyn, NY (US);

Xueling Wu, Potomac, MD (US);

Tongqing Zhou, Boyds, MD (US);

Zhi-Yong Yang, Potomac, MD (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1063 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); G01N 33/56988 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present application relates novel HIV-1 broadly neutralizing antibodies. The antibodies of the present invention are further characterized by their ability to bind epitopes from the Env proteins. The invention also provides light and heavy chain variable region sequences. Compositions for prophylaxis, diagnosis and treatment of HIV infection are provided.


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