The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Oct. 04, 2012
Applicant:

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Inventors:

Qingzhao Wang, Scarsdale, NY (US);

Keelnatham T. Shanmugam, Gainesville, FL (US);

Lonnie O'Neal Ingram, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12N 15/53 (2006.01); C12P 7/56 (2006.01); C12P 7/26 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12P 7/26 (2013.01); C12P 7/56 (2013.01); C12P 2203/00 (2013.01);
Abstract

The present invention provides methods of designing and generating glycerol dehydrogenase (GlyDH) variants that have altered function as compared to a parent polypeptide. The present invention further provides nucleic acids encoding GlyDH polypeptide variants having altered function as compared to the parent polypeptide. Host cells comprising polynucleotides encoding GlyDH variants and methods of producing lactic acids are also provided in various aspects of the invention.


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