The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Apr. 08, 2015
Applicant:

Solvotrin Therapeutics Ltd., Cork, IE;

Inventors:

John Francis Gilmer, Dublin, IE;

Mark Ledwidge, Cork, IE;

Pat O'Flynn, Cork, IE;

Shona Harmon, Dublin, IE;

Marek Radomski, Dublin, IE;

Carlos Medina Martin, Dublin, IE;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 493/04 (2013.01);
Abstract

A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C-Calkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, which can be unsubstituted or substituted with at least one nitric oxide releasing group; and/or at least one of hydroxide, —Cl, —Br, a C-Calkyl, benzyl, a C-Calkoxy, benzyloxy, —NHC(O)R, —NH, —NO, —ONO, —(CH)ONO, —OC(O)[(CH)m], cyclic ONO, —OCOArONO, —OCOAr(CH)ONOor a C-Chaloalkyl ester, wherein R is a C-Calkyl or a C-Calkoxy group, n=1-8 and m=3-10, to produce a super-aspirin effect.


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