The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Jan. 15, 2015
Applicant:
Codexis, Inc., Redwood City, CA (US);
Inventors:
Jack S Liang, San Mateo, CA (US);
Stephan Jenne, Foster City, CA (US);
Emily Mundorff, Garden City, NY (US);
Rama Voladri, Milpitas, CA (US);
James J. Lalonde, Palo Alto, CA (US);
Gjalt W. Huisman, Redwood City, CA (US);
Assignee:
Codexis, Inc., Redwood City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/00 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01); C12P 17/16 (2006.01);
U.S. Cl.
CPC ...
C12P 17/00 (2013.01); C12N 9/0006 (2013.01); C12P 17/167 (2013.01); C12Y 101/01184 (2013.01); Y02P 20/52 (2015.11);
Abstract
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize chiral compounds.