The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Dec. 24, 2009
Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Rotterdam, NL;
Johannes Adrianus Maria DE Bont, Wageningen, NL;
Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Rotterdam, NL;
Johannes Adrianus Maria De Bont, Wageningen, NL;
DSM IP ASSETS B.V., Heerlen, NL;
Abstract
The present invention relates to eukaryotic cells which have the ability to isomerize xylose directly into xylulose by transformation with nucleotide sequences encoding a xylose isomerase that has one or more specific sequence elements typical for isomerases which are functionally expressed in yeasts, such as xylose isomerases obtainable from bacteria of the generaandor a tunicate from the genus. The cell preferably is a yeast or a filamentous fungus capable of anaerobic alcoholic fermentation. The cells may further comprise one or more genetic modifications that increase the flux of the pentose phosphate pathway or, reduce unspecific aldose reductase activity. The cell preferably has the ability to produce a fermentation product such as ethanol, lactic acid, 3-hydroxy-propionic acid, β-lactam antibiotics and cephalosporins. Also provided are processes for producing these fermentation products from xylose.