The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2015

Filed:

Dec. 23, 2009
Applicants:

Heidi Hau, Lebanon, NH (US);

Charles Rice, Hopkinton, NH (US);

Chris Herring, Lebanon, NH (US);

John Mcbride, Lyme, NH (US);

Arthur J. Shaw, Iv, Grantham, NH (US);

Erin Wiswall, Danbury, NH (US);

Inventors:

Heidi Hau, Lebanon, NH (US);

Charles Rice, Hopkinton, NH (US);

Chris Herring, Lebanon, NH (US);

John McBride, Lyme, NH (US);

Arthur J. Shaw, IV, Grantham, NH (US);

Erin Wiswall, Danbury, NH (US);

Assignee:

Enchi Corporation, Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/10 (2006.01); C12P 19/14 (2006.01); C12N 9/42 (2006.01); C12N 15/74 (2006.01); C12P 7/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); C12N 9/2437 (2013.01); C12P 7/065 (2013.01); C12P 7/10 (2013.01); Y02E 50/16 (2013.01); Y02E 50/17 (2013.01);
Abstract

Thermophilic gram-positive anaerobic host cells, for example(''), express heterologous biomass degrading enzymes, such as cellulases, and are able to produce useful fermentation products from cellulose. Useful fermentation products include, for example, ethanol, acetic acid, lactic acid or CO2. In order to provide maximum expression and activity levels, biomass degrading enzymes can be expressed from codon-optimized nucleotide sequences, can be expressed under the control of a high-efficiency promoter, and/or can be fused to a signal peptide. In addition, the host cell, for example, ahost cell, can be genetically altered to further improve ethanol production, for example by disrupting the production of organic products other than ethanol.


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