The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Oct. 21, 2011
Applicants:

Olle Hernell, Umeå, SE;

Birgitta Olsson, Stenhamra, SE;

Patrik Strömberg, Sollentuna, SE;

Lennart Svensson, Solna, SE;

Kristina Timdahl, Tullinge, SE;

M{hacek Over (A)}rten Vågerö, Saltsjö-Boo, SE;

Maria Öhman, Piteå, SE;

Inventors:

Olle Hernell, Umeå, SE;

Birgitta Olsson, Stenhamra, SE;

Patrik Strömberg, Sollentuna, SE;

Lennart Svensson, Solna, SE;

Kristina Timdahl, Tullinge, SE;

M{hacek over (a)}rten Vågerö, Saltsjö-Boo, SE;

Maria Öhman, Piteå, SE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 9/20 (2006.01); A23L 1/00 (2006.01);
U.S. Cl.
CPC ...
C12Y 301/01003 (2013.01); A23L 1/00 (2013.01); A61K 38/465 (2013.01); C12Y 301/01013 (2013.01);
Abstract

The present invention relates to a method to increase the growth velocity of a human infant, said method comprising the enteral administration to said infant of recombinant human bile-salt-stimulated lipase (rhBSSL). Such method has particular utility for underweight or preterm human infants, particular those in medical need of increasing their growth velocity. The invention also relates to compositions, including infant feeds, kits, packaged-pharmaceutical-products and pharmaceutical compositions, and also to methods to prepare infant feeds. In another aspect, the present invention relates to methods to: (X) protect the small bowel mucosa of a human infant from damage; to (Y) protect an immature intestinal epithelium of a human infant from the deleterious effects of incompletely digested and/or excess fat and/or lipid; and/or to (Z) limit accumulation of incompletely digested and/or excess fat and/or lipid in the ileum of a human infant; said methods in each case comprising the step of enteral administration of rhBSSL.


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