The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Nov. 14, 2007
Applicants:

Tapas Das, Worthington, OH (US);

Pradip Mukerji, Columbus, OH (US);

Padmavathy Krishnan, Hilliard, OH (US);

Amanda E. Leonard, Columbus, OH (US);

Suzette L. Pereira, Westerville, OH (US);

Inventors:

Tapas Das, Worthington, OH (US);

Pradip Mukerji, Columbus, OH (US);

Padmavathy Krishnan, Hilliard, OH (US);

Amanda E. Leonard, Columbus, OH (US);

Suzette L. Pereira, Westerville, OH (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 9/00 (2006.01); C12P 7/64 (2006.01); C12N 1/20 (2006.01); C12N 1/12 (2006.01); C12N 1/00 (2006.01); C12N 15/00 (2006.01); C12N 15/20 (2006.01); C07H 21/04 (2006.01); A01K 67/00 (2006.01); A01H 5/00 (2006.01); C12N 15/82 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); C12N 15/8247 (2013.01);
Abstract

The subject invention relates to the identification of a gene involved in the elongation of polyunsaturated fatty acids containing unsaturation at the carbon 9 position (i.e., 'Δ9-elongase') and to uses thereof. In particular, Δ9-elongase may be utilized, for example, in the conversion of linoleic acid (LA, 18:2n-6) to eicosadienoic acid (EDA, 20:2n-6). The production of dihomo-γ-linolenic acid (DGLA, 20:3n-6) from eicosadienoic acid (EDA, 20:2n-6), and arachidonic acid (AA, 20:4n-6) from dihomo-γ-linolenic acid (DGLA, 20:3n-6) is then catalyzed by Δ8-desaturase and Δ5-desaturase, respectively. AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.


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