The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2014

Filed:

Feb. 27, 2012
Applicants:

Brett Justin West, Cedar Hills, UT (US);

Claude Jarakae Jensen, Cedar Hills, UT (US);

Afa Kehaati Palu, American Fork, UT (US);

Shixin Deng, Lehi, UT (US);

Jeffery A. Wasden, Springville, UT (US);

Inventors:

Brett Justin West, Cedar Hills, UT (US);

Claude Jarakae Jensen, Cedar Hills, UT (US);

Afa Kehaati Palu, American Fork, UT (US);

Shixin Deng, Lehi, UT (US);

Jeffery A. Wasden, Springville, UT (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 36/45 (2006.01); A61K 36/87 (2006.01); A61K 36/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fortified food and dietary supplement products may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with plant products and iridoids. A study was performed to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin In the 2,2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an ICof 3.8 μL/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats. In a dose-dependent manner, the composition reduced abnormal weight gain, blood glucose levels, and serum advanced glycation end products (AGEs), as well as improved immunity via increased T cell counts and CD4+/CD8ratios.


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