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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8338365 B1

PDFFull Text
Expired
Date of Patent:
Dec. 25, 2012

Filed:

Feb. 06, 2012

Inhibiting integrin receptor binding with non-native monomeric disintegrin or monomeric disintegrin domains

Applicants:

Radu O. Minea, Arcadia, CA (US);

Francis S. Markland, Jr., Manhattan Beach, CA (US);

Inventors:

Radu O. Minea, Arcadia, CA (US);

Francis S. Markland, Jr., Manhattan Beach, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorneys:

Foley & Lardner LLP

Antoinette F. Konski

Primary Examiner:

Suzanne M Noakes

Assistant Examiner:

Jae W Lee

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/36 (2006.01); A61P 35/00 (2006.01); A61P 7/02 (2006.01); A61P 35/04 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to methods of inhibiting binding between a cell expressing integrin receptors specific for one or more integrins selected from the group consisting of αIIbβ3, αvβ3, αvβ5, or α5β1, said method comprising contacting the cell with a monomeric disintegrin or monomeric disintegrin domain which comprises a C-terminal sequence non-native to the disintegrin or disintegrin domain, said C-terminal sequence encoding a functional integrin-binding loop.

Find Patent Forward Citations

Minea, Radu. (2012). Inhibiting integrin receptor binding with non-native monomeric disintegrin or monomeric disintegrin domains (U.S. Patent No. 8338365). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8338365

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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