The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2012

Filed:

Sep. 30, 2010
Applicants:

Hector F. Deluca, Deerfield, WI (US);

Agnieszka Glebocka, Madison, WI (US);

Lori A. Plum, Arena, WI (US);

Margaret Clagett-dame, Deerfield, WI (US);

Rafal R. Sicinski, Warsaw, PL;

Inventors:

Hector F. DeLuca, Deerfield, WI (US);

Agnieszka Glebocka, Madison, WI (US);

Lori A. Plum, Arena, WI (US);

Margaret Clagett-Dame, Deerfield, WI (US);

Rafal R. Sicinski, Warsaw, PL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/59 (2006.01); C07C 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

19-nor-vitamin D analogs having an additional cyclopentene ring connecting carbon 1 and carbon 2, or connecting carbon 3 and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro activities, making them therapeutic agents for the treatment or prophylaxis of some types of cancers, particularly leukemia, colon cancer, breast cancer, skin cancer or prostate cancer.


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