The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

Mar. 30, 2011
Applicants:

Doug Lies, Parker, CO (US);

Stephanie Porter-scheinman, Conifer, CO (US);

Julie Kelly, Denver, CO (US);

Catherine Asleson Dundon, Englewood, CO (US);

Aristos Aristidou, Highlands Ranch, CO (US);

Andrew Hawkins, Parker, CO (US);

Inventors:

Doug Lies, Parker, CO (US);

Stephanie Porter-Scheinman, Conifer, CO (US);

Julie Kelly, Denver, CO (US);

Catherine Asleson Dundon, Englewood, CO (US);

Aristos Aristidou, Highlands Ranch, CO (US);

Andrew Hawkins, Parker, CO (US);

Assignee:

Gevo, Inc., Englewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/16 (2006.01); C12N 15/00 (2006.01); C12N 15/87 (2006.01); C12N 15/74 (2006.01); C12P 7/16 (2006.01); C12P 1/02 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of theclade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.


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