The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Aug. 13, 2007
Scott Powers, Cold Spring Harbor, NY (US);
Lars Zender, Cold Spring Harbor, NY (US);
Rebecca A. Kohnz, Cold Spring Harbor, NY (US);
Scott W. Lowe, Cold Spring Harbor, NY (US);
Scott Powers, Cold Spring Harbor, NY (US);
Lars Zender, Cold Spring Harbor, NY (US);
Rebecca A. Kohnz, Cold Spring Harbor, NY (US);
Scott W. Lowe, Cold Spring Harbor, NY (US);
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Abstract
The invention provides methods for diagnosing cancers in humans by detecting DNA amplifications in chromosomal region 8p22, which encompasses the FGF-20 gene and the EFHA2 gene. Also provided are cancer treatment methods using inhibitors of FGF-20 and EFHA2. The invention also provides methods for promoting successful regeneration of liver function. These methods can be used therapeutically to improve liver function following transplantation in both recipient and donor subjects.