The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2010
Filed:
Oct. 21, 2004
Robert Plourde, Jr., Chapel Hill, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
Melwyn Anthony Abreo, Jamul, CA (US);
Lorenzo Josue Alfaro-lopez, San Marcos, CA (US);
Yangbo Feng, Palm Beach Gardens, FL (US);
Tatyana V. Khasanova, San Diego, CA (US);
Mark W. Holladay, San Diego, CA (US);
Christopher S. Crean, Pittsboro, NC (US);
Robert Plourde, Jr., Chapel Hill, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
Melwyn Anthony Abreo, Jamul, CA (US);
Lorenzo Josue Alfaro-Lopez, San Marcos, CA (US);
Yangbo Feng, Palm Beach Gardens, FL (US);
Tatyana V. Khasanova, San Diego, CA (US);
Mark W. Holladay, San Diego, CA (US);
Christopher S. Crean, Pittsboro, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
Abstract
The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor antagonist. The methods of the present invention are useful in reducing pain, such as traumatic pain, neuropathic pain, organ pain and/or pain associated with diseases. The P2X receptor antagonists useful for this invention are non-nucleotide compounds of general Formula I. Compounds of Formula I can be used alone to treat pain. Compounds of Formula I can also be used in conjunction with other therapeutic agents or adjunctive therapies commonly used to treat pain, thus enhancing the therapeutic effect of pain reduction.