The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2009

Filed:

May. 10, 2007
Applicants:

Balkrishen Bhat, Carlsbad, CA (US);

Jie Xia, Carlsbad, CA (US);

Punit P. Seth, San Marcos, CA (US);

Guillermo Vasquez, Oceanside, CA (US);

Michael T. Migawa, Carlsbad, CA (US);

Charles Allerson, San Diego, CA (US);

Thazha P. Prakash, Carlsbad, CA (US);

Eric E. Swayze, Carlsbad, CA (US);

Inventors:

Balkrishen Bhat, Carlsbad, CA (US);

Jie Xia, Carlsbad, CA (US);

Punit P. Seth, San Marcos, CA (US);

Guillermo Vasquez, Oceanside, CA (US);

Michael T. Migawa, Carlsbad, CA (US);

Charles Allerson, San Diego, CA (US);

Thazha P. Prakash, Carlsbad, CA (US);

Eric E. Swayze, Carlsbad, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds and methods of using them for preparing bicyclic nucleosides. The bicyclic nucleosides are useful for preparing chemically modified oligomeric compounds. Oligomeric compounds comprising these bicyclic nucleosides have enhanced properties such as increased nuclease resistance.


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