The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Feb. 26, 2004
Jonathan M. Rothberg, Guilford, CT (US);
Joel S. Bader, Paris, FR;
Scott B. Dewell, New Haven, CT (US);
Keith Mcdade, Clinton, CT (US);
John W. Simpson, Madison, CT (US);
Jan Berka, New Haven, CT (US);
Christopher M. Colangelo, Pawcatuck, CT (US);
Jonathan M. Rothberg, Guilford, CT (US);
Joel S. Bader, Paris, FR;
Scott B. Dewell, New Haven, CT (US);
Keith McDade, Clinton, CT (US);
John W. Simpson, Madison, CT (US);
Jan Berka, New Haven, CT (US);
Christopher M. Colangelo, Pawcatuck, CT (US);
454 Life Sciences Corporation, Branford, CT (US);
Abstract
Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.