The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2006
Filed:
Aug. 11, 2003
S. Christopher Davis, San Francisco, CA (US);
John H. Grate, Los Altos, CA (US);
David R. Gray, Walnut Creek, CA (US);
John M. Gruber, Mountain View, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Steven K. MA, Foster City, CA (US);
Lisa M. Newman, Redwood City, CA (US);
Roger Sheldon, Rijswijk, NL;
LI a Wang, Palo Alto, CA (US);
S. Christopher Davis, San Francisco, CA (US);
John H. Grate, Los Altos, CA (US);
David R. Gray, Walnut Creek, CA (US);
John M. Gruber, Mountain View, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Steven K. Ma, Foster City, CA (US);
Lisa M. Newman, Redwood City, CA (US);
Roger Sheldon, Rijswijk, NL;
Li A Wang, Palo Alto, CA (US);
Codexis, Inc., Redwood City, CA (US);
Abstract
The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives.