The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2006
Filed:
Aug. 02, 2002
Leonid Romanovich Ptitsyn, Moscow, RU;
Sergey Vasil'evich Smirnov, Moscow, RU;
Irina Borisovna Altman, Moscow, RU;
Anna Eugenievna Novikova, Moscow, RU;
Veronika Aleksandrovna Kotliarova, Moscow, RU;
Mikhail Markovich Gusyatiner, Moscow, RU;
Yulia Georgievna Rostova, Moscow, RU;
Tatyana Abramovna Yampolskaya, Moscow, RU;
Leonid Romanovich Ptitsyn, Moscow, RU;
Sergey Vasil'evich Smirnov, Moscow, RU;
Irina Borisovna Altman, Moscow, RU;
Anna Eugenievna Novikova, Moscow, RU;
Veronika Aleksandrovna Kotliarova, Moscow, RU;
Mikhail Markovich Gusyatiner, Moscow, RU;
Yulia Georgievna Rostova, Moscow, RU;
Tatyana Abramovna Yampolskaya, Moscow, RU;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5'-monophosphate (UMP), cytidine and cytidine 5′-monophosphate (CMP) are produced using a bacterium belonging to the genusharboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate synthetase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 9, and feedback inhibition by uridine 5′-monophosphate in the bacterium is desensitized.