The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2005
Filed:
Jul. 01, 1999
James M. Hogle, Newton, MA (US);
Harmon J. Zuccola, Brookline, MA (US);
David Filman, Auburndale, MA (US);
Carl Elkin, Cambridge, MA (US);
James M. Hogle, Newton, MA (US);
Harmon J. Zuccola, Brookline, MA (US);
David Filman, Auburndale, MA (US);
Carl Elkin, Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
This invention relates to HDAg peptides, including mutants, derivatives fragments and fusion molecules, including fusion proteins, coiled-coil oligomers, nucleic acid molecules, vectors comprising HDAg nucleic acid molecules, cells comprising said molecules, methods of multivalent expression and association of binding moieties of HDAg fusion molecules, and methods of use involving the molecules. The molecules are particularly useful as a framework for multivalent display via formation of C-terminal and/or N-terminal fusion proteins or via chemical coupling to chemically reactive sidechains, e.g. cysteine residues.