The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1998
Filed:
Nov. 06, 1996
Applicant:
Inventors:
Renata Grifantini, Milano, IT;
Giuliano Galli, S. Donato Milanese, IT;
Giovanna Carpani, Sergnano, IT;
Guido Grandi, Segrate, IT;
Assignee:
Eniricerche S.p.A., Milan, IT;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435106 ; 43525231 ; 43525233 ; 4353201 ; 935 22 ;
Abstract
In an improved process for the preparation of D-.alpha.-amino acids by the stereoselective conversion of racemic mixtures of 5-substituted hydantoins with an enzymatic system produced by a microorganism, the improvement consists in the fact that a microorganism is used which is transformed with the plasmid pSM700 cultivated at a temperature of between 20.degree. C. and 28.degree. C. The use of this microorganism allows an improvement in the expression of the enzymatic system and an increase in the conversion rate of the racemic hydantoin to D-.alpha.-amino acid.