The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 1997
Filed:
Oct. 17, 1994
Applicant:
Inventors:
Vladimir D Axelrod, New York, NY (US);
Fred R Kramer, New York, NY (US);
Paul M Lizardi, Cuernavaca, MX;
Donald R Mills, Englewood, NJ (US);
Assignee:
The Trustees of Columbia University in the City of New York, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C12P / ; C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435-4 ; 435-71 ; 435 15 ; 435 14 ; 435 9121 ; 4351723 ; 4353201 ; 536 221 ; 536 241 ; 935 77 ; 935 78 ;
Abstract
This invention relates to the use of functional reporter molecules in the detection and measurement of targets in a sample. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target.