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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5424184 B1

PDFFull Text
Date of Patent:
Jun. 13, 1995

Filed:

May. 08, 1991

Dna sequence-based hla class i typing method

Applicant:
Inventors:

Pedro Santamaria, Minneapolis, MN (US);

Michael T Boyce-Jacino, Saint Paul, MN (US);

Jose Barbosa, Roseville, MN (US);

Stephen S Rich, Saint Paul, MN (US);

Anthony J Faras, Long Lake, MN (US);

Assignee:

Regents of the University of Minnesota, , MN (US);

Attorney:

Rae-Venter; Barbara

Primary Examiner:

Robert A Wax

Assistant Examiner:

Rebecca Prouty

Int. Cl.
CPC ...
C12Q / ; C12Q / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 15 ; 435 912 ; 435 9121 ; 536 2433 ; 935-8 ; 935 17 ; 935 18 ; 935 77 ; 935 78 ;
Abstract

The present invention provides a process for determining genotypes in highly polymorphic systems by polymerase chain reaction amplification of cDNA or genomic DNA and direct sequencing polymerase chain reaction products using oligonucleotide primers. More specifically, Class I HLA genotypes can be unambiguously determined in any subject in 16-24 hours by direct sequencing of HLA-A, HLA-B, and HLA-C transcripts enzymatically amplified and sequenced using a limited number of selected oligonucleotides.

Find Patent Forward Citations

Santamaria, Pedro. (1995). Dna sequence-based hla class i typing method (U.S. Patent No. 5424184). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5424184

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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