The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 1993

Filed:

Sep. 14, 1989
Applicant:
Inventors:

Lindley C Blair, Los Angeles, CA (US);

Raju K Koduri, LaJolla, CA (US);

Jar-How Lee, Palos Verdes Estates, CA (US);

Joachim L Weickmann, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
43525233 ; 435 691 ; 4351723 ; 435243 ; 435256 ; 4353201 ; 536 236 ; 935 10 ;
Abstract

Genes are disclosed which are capable of directing the synthesis in a selected host microorganism of thaumatin I polypeptides having improved taste characteristics characterized by having the amino acid sequence of natural thaumatin I including a lysine amino acid residue substituted for asparagine in the 46th position from the amino terminal end, an aspartate amino acid residue substituted for asparagine in the 113th position from the amino terminal end and an aspartate amino acid residue substituted for lysine at either the 97th or 137th residue from the amino terminal end.


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