The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 1992
Filed:
Sep. 30, 1988
Applicant:
Inventors:
Paul M Lizardi, Cuernavaca, MX;
Fred R Kramer, New York, NY (US);
Sanjay Tyagi, New York, NY (US);
Cesar E Guerra, New York, NY (US);
Hilda M Buyoli, Mexico City, MX;
Assignees:
The Public Health Research Institute, New York, NY (US);
The Salk Instiute for Biological Studies, San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C12Q / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
536 27 ; 536 26 ; 536 28 ; 536 29 ; 435-6 ; 935 77 ; 935 78 ; 436501 ; 436 94 ;
Abstract
A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.