The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2026

Filed:

Sep. 08, 2022
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Thomas Baker, San Diego, CA (US);

Kevin Early, San Diego, CA (US);

Siqi Zhang, San Diego, CA (US);

Rachel Abaskharon, San Diego, CA (US);

Anmiv Prabhu, San Diego, CA (US);

Patrick Wen, Encinitas, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 15/1433 (2024.01); G01N 15/10 (2024.01); G01N 15/1434 (2024.01);
U.S. Cl.
CPC ...
G01N 15/1433 (2024.01); G01N 15/1012 (2013.01); G01N 2015/1452 (2013.01);
Abstract

Generation and use of a focus quality metric that is intensity independent is described. In one example, the focus quality metric is generated by acquiring an image, such as an image of a patterned surface of a flow cell, and processing all or part (e.g., a sub-region or sub-image) to generate a Fourier transform of the respective image data. By way of example, in one embodiment a discrete Fourier transform may be applied to a sub-region of an image of a patterned flow cell surface. A focus quality metric that is intensity independent may be derived from the Fourier transform of the image data.


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