The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Mar. 17, 2022
Jiangnan University, Wuxi, CN;
Bo Yang, Wuxi, CN;
Wei Chen, Wuxi, CN;
Zhexin Fan, Wuxi, CN;
Qixiao Zhai, Wuxi, CN;
Gang Wang, Wuxi, CN;
Wenwei Lu, Wuxi, CN;
Shumao Cui, Wuxi, CN;
Jianxin Zhao, Wuxi, CN;
Hao Zhang, Wuxi, CN;
Abstract
Described is astrain for relieving rheumatoid arthritis and application thereof, belonging to the technical field of microorganisms. Described is astrain CCFM1078 possessing the effect of relieving rheumatoid arthritis, and shown to: promote secretion of anti-inflammatory factor IL-10 from RAW264.7 cells; reduce joint thickness, clinical score, and incidence of rats with rheumatoid arthritis; decrease levels of the pro-inflammatory cytokines TNFα and IL-1β in the serum of rats with rheumatoid arthritis; regulate the content of short-chain fatty acids in the feces of rats with rheumatoid arthritis; decrease the proportion of Th17 cells in the mesenteric lymph nodes of rats with rheumatoid arthritis; and reduce secretion of pro-inflammatory factor IL-6 from synovial cells.