The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2025

Filed:

Feb. 09, 2021
Applicant:

Icemos Technology Limited, Belfast, GB;

Inventors:

Samuel J. Anderson, Tempe, AZ (US);

Hugh J. Griffin, Belfast, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/414 (2006.01); G01N 27/327 (2006.01); G01N 33/539 (2006.01);
U.S. Cl.
CPC ...
G01N 27/4145 (2013.01); G01N 27/3272 (2013.01); G01N 27/4146 (2013.01); G01N 33/539 (2013.01);
Abstract

An atomic level deposition for mass functionalization of a cavity filled with a pathogen sensitive antibody reagent to functionalize each biosensor using atomic level vapor phase deposition enables high volume production of this sensor technology. A biosensor has a first substrate and a second substrate with a cavity formed in the first substrate to form a membrane. Holes are formed through the second substrate. An aluminum oxide layer is formed over the cavity and into the holes to form cores. The cavity is filled with a pathogen sensitive antibody reagent. A biofluid sample with the pathogen is deposited over the membrane. The biofluid is drawn through the cores to mix with the antibody reagent. The antibodies combine with the pathogen to change the impedance along the current path. The presence of the pathogen changes the ionic current flow through the biosensor for a positive detection of the pathogen.


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