The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Oct. 10, 2021
Haiqin Chen, Wuxi, CN;
BO Yang, Wuxi, CN;
He Gao, Wuxi, CN;
Jianxin Zhao, Wuxi, CN;
Yongquan Chen, Wuxi, CN;
Hao Zhang, Wuxi, CN;
Wei Chen, Wuxi, CN;
Haiqin Chen, Wuxi, CN;
Bo Yang, Wuxi, CN;
He Gao, Wuxi, CN;
Jianxin Zhao, Wuxi, CN;
Yongquan Chen, Wuxi, CN;
Hao Zhang, Wuxi, CN;
Wei Chen, Wuxi, CN;
Jiangnan University, Wuxi, CN;
Abstract
Disclosed is linoleic acid isomerases and their application in production of conjugated linoleic acid, which belongs to the technical fields of protein engineering and microbial engineering. The linoleic acid isomerase derived fromis used to produce the conjugated linoleic acid. The recombinantcontaining the linoleic acid isomerase of the invention is added into a reaction system containing linoleic acid and react for 3 h to produce conjugated linoleic acids. The conversion rate of the conjugated linoleic acid of the invented method ranges from 12.1% to 42.1%, and the percentage of cis9, trans11-CLA in the conjugated linoleic acid can reach 84.3% to 89.1%. The invention provides a method for using microorganisms to produce conjugated linoleic acids with high safety and yield where cis9, trans11-CLA isomer is the major form in the conjugated linoleic acid products.