The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2023

Filed:

Oct. 23, 2018
Applicants:

Kumiai Chemical Industry Co., Ltd., Taito-Ku, JP;

K.i Chemical Industry Co., Ltd., Iwata, JP;

Okayama Prefectural Government, Okayama, JP;

Inventors:

Toshinobu Yamazaki, Taito-Ku, JP;

Nobutoshi Myojo, Taito-Ku, JP;

Shingo Hattori, Iwata, JP;

Tatsuya Horiuchi, Iwata, JP;

Akira Kawaguchi, Fukuyama, JP;

Namiko Kirino, Akaiwa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/00 (2006.01); C12N 1/04 (2006.01); A01N 63/20 (2020.01); C12N 1/20 (2006.01); A61K 35/74 (2015.01); C12R 1/41 (2006.01);
U.S. Cl.
CPC ...
C12N 1/04 (2013.01); A01N 63/20 (2020.01); A61K 35/74 (2013.01); C12N 1/20 (2013.01); C12N 1/205 (2021.05); C12R 2001/41 (2021.05);
Abstract

Provided herein is a method for producing a lyophilized composition of viable cells ofbacteria having high viable cell viability, and a lyophilized composition of viable cells ofbacteria having desirable long-storage survivability, among others. The lyophilized composition of viable cells ofbacteria having high viable cell viability and desirable long-storage survivability can be obtained when a composition containing viable cells ofbacteria and more than 10 mass % moisture is lyophilized to bring the moisture content to 10 mass %, and the drying is ended before the moisture content becomes less than 5 mass % so that the composition after the lyophilization contains the viable bacteria and 5 to 10 mass % of moisture.


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