The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Jul. 19, 2018
Jiangnan University, Wuxi, CN;
Wei Chen, Wuxi, CN;
Gang Wang, Wuxi, CN;
Eryin Wang, Wuxi, CN;
Jianxin Zhao, Wuxi, CN;
Hao Zhang, Wuxi, CN;
Jiangnan University, Wuxi, CN;
Abstract
The present invention relates to the technical field of microbes, in particular to awhich can significantly inhibit the occurrence of colorectal cancer, and its use thereof. Thestrain CCFM164 has a deposit number CGMCC No. 14520, which has a good tolerance to gastric acid and bile salts, significantly alleviate the level of colorectal inflammation in colorectal cancer model mice, and can reduce the number of tumors in the colon and rectum of the model mice by regulating the Notch1, Notch2 signaling pathway and the expression of VEGFR2 molecule in colorectal tissue. In addition, theCCFM164 can also improve the intestinal flora population and short-chain fatty acid levels in the intestine. TheCCFM164 is used to prepare a fermented food for the inhibition of the occurrence of colorectal cancer with wild applications.