The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Aug. 02, 2018
Dovetail Genomics, Llc, Santa Cruz, CA (US);
Christopher John Troll, Santa Cruz, CA (US);
Martin P. Powers, San Francisco, CA (US);
Nicholas H. Putnam, Waltham, MA (US);
Marco Blanchette, Santa Cruz, CA (US);
Paul Hartley, San Jose, CA (US);
DOVETAIL GENOMICS, LLC, Scotts Valley, CA (US);
Abstract
The disclosure provides methods to isolate genome or chromosome level structural information from preserved samples. In some cases, samples preserved under conditions where long-range nucleic acid information is believed to be irreparably lost, such as FFPE samples, are treated to recover nucleic acid-protein complexes stabilized as part of the sample preservation process. The complexes are processed so as to recover information regarding which nucleic acids are bound to a common complex, and the information is used to recover genomic structural information.