The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Nov. 22, 2017
Harpoon Therapeutics, Inc., South San Francisco, CA (US);
Patrick Baeuerle, Gauting, DE;
Jeanmarie Guenot, San Francisco, CA (US);
Holger Wesche, San Francisco, CA (US);
Robert B. Dubridge, Belmont, CA (US);
Bryan D. Lemon, Mountain View, CA (US);
Richard J. Austin, San Francisco, CA (US);
Pui Seto, San Carlos, CA (US);
HARPOON THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
Provided herein are prostate specific membrane antigen (PSMA) targeting trispecific proteins comprising a domain binding to CD3, a half-life extension domain, and a domain binding to PSMA. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such PSMA targeting trispecific proteins. Also disclosed are methods of using the disclosed PSMA targeting trispecific proteins in the prevention, and/or treatment diseases, conditions and disorders.