The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2020

Filed:

Jun. 19, 2018
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Mathew G. Miller, San Carlos, CA (US);

Chinping Chng, Menlo Park, CA (US);

Oscar Alvizo, Fremont, CA (US);

Melissa Ann Mayo, Foster City, CA (US);

James Nicholas Riggins, San Francisco, CA (US);

Xiang Yi, Foster City, CA (US);

Jonathan S. Penfield, Truckee, CA (US);

Gjalt W. Huisman, Redwood City, CA (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1247 (2013.01); C12P 19/34 (2013.01); C12Y 207/07006 (2013.01);
Abstract

The present invention provides engineered T7 RNA polymerase variants and compositions thereof. These variants have been evolved for selective incorporation of the symmetrical capped GTP analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for using the variants provided herein. The present invention further provides for the use of the compositions provided herein.


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