IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10421727 B1

PDFFull Text
Date of Patent:
Sep. 24, 2019

Filed:

Sep. 06, 2017

Compounds useful as modulators of trpm8

Applicant:

Firmenich Incorporated, Plainsboro, NJ (US);

Inventors:

Lyudmyla Chumakova, San Diego, CA (US);

Andrew Patron, San Marcos, CA (US);

Chad Priest, Cardiff, CA (US);

Donald Karanewsky, Escondido, CA (US);

Rachel Kimmich, San Diego, CA (US);

Brant Clayton Boren, San Diego, CA (US);

Jeffrey Robert Hammaker, San Diego, CA (US);

Volodymyr Chumakov, San Diego, CA (US);

Wen Zhao, San Diego, CA (US);

Alain Noncovich, San Diego, CA (US);

Jane Ung, San Diego, CA (US);

Assignee:

FIRMENICH INCORPORATED, Plainsboro, NJ (US);

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

Kamal A Saeed

Int. Cl.
CPC ...
C07D 231/20 (2006.01); C07D 403/06 (2006.01); C07D 401/06 (2006.01); C07D 333/22 (2006.01); C07D 239/62 (2006.01); C07D 239/22 (2006.01); C07D 235/02 (2006.01); C07D 233/78 (2006.01); C07D 213/50 (2006.01); C07D 207/26 (2006.01); C07D 207/32 (2006.01); C07D 405/06 (2006.01); C07C 233/31 (2006.01); A23L 33/10 (2016.01); A23L 2/52 (2006.01); C07D 409/06 (2006.01); C07D 207/333 (2006.01);
U.S. Cl.
CPC ...
C07D 231/20 (2013.01); A23L 2/52 (2013.01); A23L 33/10 (2016.08); C07C 233/31 (2013.01); C07D 207/26 (2013.01); C07D 207/32 (2013.01); C07D 207/333 (2013.01); C07D 213/50 (2013.01); C07D 233/78 (2013.01); C07D 235/02 (2013.01); C07D 239/22 (2013.01); C07D 239/62 (2013.01); C07D 333/22 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); A23V 2002/00 (2013.01); C07C 2601/04 (2017.05); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05);
Abstract

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

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