The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Feb. 16, 2015
Applicant:

Lesaffre ET Compagnie, Paris, FR;

Inventors:

Thomas Desfougeres, Neuville en Ferrain, FR;

Georges Pignede, Marcq en Baroeul, FR;

Jennifer Techel, Le Bizet, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/36 (2006.01); C12N 15/81 (2006.01); C12R 1/865 (2006.01); C12P 7/10 (2006.01); C12N 9/12 (2006.01); C12N 9/92 (2006.01);
U.S. Cl.
CPC ...
C12N 1/36 (2013.01); C12N 9/1205 (2013.01); C12N 9/92 (2013.01); C12N 15/81 (2013.01); C12P 7/10 (2013.01); C12R 1/865 (2013.01); C12Y 207/01006 (2013.01); C12Y 207/01017 (2013.01); C12Y 503/01005 (2013.01); Y02E 50/16 (2013.01); Y02E 50/17 (2013.01);
Abstract

The present invention relates to a method for obtaining a strain capable of efficiently propagating in a low nutritive potential medium, capable of metabolizing pentoses and of resisting fermentation inhibitors, comprising the following steps; a) growth of a strain of recombinant yeast with a strain of wild yeast lacking any impairments, the recombinant yeast strain comprising at least one copy of an exogenous gene of xylose isomerase and at least one additional copy of a gene of D-xylulokinase included in the genome and linked to a single sexual characteristic of the strain, b) at least two cycles of genome shuffling by sporulation and or random hybridization, c) selection of the population obtained in step b) according to a suitability criterion of the strains to metabolize xylose, d) selection of the population obtained in step c) according to a suitability criterion of the strains to grow in a Pref type medium, a medium with low nutritive value. The invention also relates to a cell, a yeast or a strain of recombinant yeast obtained according to the method, and to the use of such a cell for the production of bioethanol.


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