The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Oct. 17, 2018
Applicant:
Enzypep B.v., Galeen, NL;
Inventors:
Peter Jan Leonard Mario Quaedflieg, Geleen, NL;
Timo Nuijens, Geleen, NL;
Jan Metske Van Der Laan, Breda, NL;
Dirk Barend Janssen, Groningen, NL;
Ana Toplak, Groningen, NL;
Bian Wu, Groningen, NL;
Assignee:
ENZYPEP B.V., Geleen, NL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 (2006.01); C07K 1/02 (2006.01); C12P 21/02 (2006.01); C12N 9/54 (2006.01); C07K 1/36 (2006.01);
U.S. Cl.
CPC ...
C07K 1/026 (2013.01); C07K 1/36 (2013.01); C12N 9/54 (2013.01); C12P 21/02 (2013.01); C12Y 304/21062 (2013.01);
Abstract
The invention relates to a method for enzymatically synthesizing an (oligo)peptide, comprising coupling (a) an (oligo)peptide C-terminal ester or thioester and (b) an (oligo)peptide nucleophile having an N-terminally unprotected amine, Further, the invention relates to an enzyme suitable for use as a catalyst in a method of the invention.