The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Feb. 01, 2016
Symrise Ag, Holzminden, DE;
Gerhard Krammer, Holzminden, DE;
Jakob Peter Ley, Holzminden, DE;
Katrin Geißler, Einbeck, DE;
Torsten Geißler, Einbeck, DE;
Frauke Gomoll, St. Ingbert, DE;
Peter Welters, Nettetal, DE;
Guido Jach, Nettetal, DE;
Ludger Wessjohann, Halle, DE;
SYMRISE AG, Holzminden, DE;
Abstract
The invention relates to providing both fermentative and biotechnological methods for producing 3,4-methylized cinnamic acids, 3,4-methylized cinnamic acid esters, 3,4-dimethoxyphenethylamine, and 4-methylized cinnamic acid amides using a 4'-O-methyltransferase, optionally in combination with further enzymes, wherein the enzymes are selected by means of metabolic engineering and operation have been adapted by targeted optimization, and compositions obtained by means of the method. The invention further relates to vector systems, recombinant microorganisms or fungi, and specific nucleic acid segments and polypeptides.